The Combination Therapy is the suggested way to increase treatment efficacy, to prevent the development of drug resistance, and to reduce the duration of treatment. It uses more than one medication or modality. Typically, the term refers to using multiple therapies to treat a single disease, and often all the therapies are pharmaceutical (although it can also involve non-medical therapy, such as the combination of medications and talk therapy to treat depression). Combination Therapy is very useful and effective.